GenomeConnect

Samatha Mathew 22 April 2021 All living beings possess a genetic material which contains the information for making up that being. The COVID-19 causing coronavirus SARS-CoV-2 is a virus with a genetic material made of a chemical molecule called ribonucleic acid or RNA- which directs the production of proteins for the survival of the virus. As a basic unit of life multiplies, its genetic material is also manufactured that many times. This can lead to minute changes in the genetic material with each turn of copying. The same is true for the SARS-CoV-2 RNA genetic material. Since there are millions of copies of the virus being multiplied even within a single patient, the virus may be changing fast, or mutating, in other terms. The more the virus stays in circulation, like it has been since 2019 now, the more the number of changes it acquires in its genetic material. Now why does this matter? Our arsenal against the SARS-CoV-2 contains many tools based on its RNA sequence (a string of che

Maple Syrup Urine Disease

Molnupiravir - what we need to know

Sahana S 10-01-2022 What is Molnupiravir? Molnupiravir (MK-4482, EIDD-2801), was initially developed by the Drug Innovation ventures at Emory University. This was later licensed by the Ridgeback therapeutics in partnership with Merck & Co, USA. Molnupiravir’s active compound, N4-hydroxycytidine (NHC) has been known and studied for decades. The antiviral drug was first developed to treat influenza and is now being repurposed to treat COVID-19. The drug was approved for emergency use authorization (EUA) by the Medicines and Healthcare products Regulatory Agency (MHRA), United Kingdom on November 4, 2021 for treating COVID19 patients. On 23rd December 2021, US-Food and Drug administration (FDA) approved EUA for molnupiravir. In continuation to that, India has also approved the drug for treating the adults who have a high progression of COVID-19 infection. What is an Emergency use Authorization (EUA)? Emergency Use Authorization (EUA) is an authority given to US-FDA which allows

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India Earns Genome stripes

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